Description
Advanced Transdermal Cell Activation: The Science of IDENEL
Key Product Benefits of IDENEL Revitalizing Nourishing Cream
- The use of micro-spicules enables the transport of ingredients, ensuring full bioavailability without damaging the skin or requiring any downtime.
- To target wrinkle reduction, it softens expression lines in the sensitive areas around the eyes and mouth.
- It increases collagen density by promoting natural elastogenesis and stimulating fibroblast proliferation.
- The luminosity and hue are corrected by fading away age spots, hyperpigmentation, and dullness, thus giving the skin a more refreshed appearance.
- It strengthens the lipid barriers to prevent transepidermal water loss (TEWL) and exposure to environmental stressors.
Key Scientific Innovations
- The Altum® Peptide and RaphiTox™ Technology uses patented microscopic bio-spicules, derived from natural ocean sponges, that are chemically bonded to active peptides. When massaged in, tiny spicules sink into the outer layers of your skin to drop active ingredients right where they’re needed most—stimulating collagen, activating fibroblasts, and renewing skin from within.
- SingGreen-NBG, together with adenosine, is a patented antioxidant complex that helps accelerate the synthesis of structural proteins and results in visible smoothing of fine lines around the eyes, forehead, and mouth.
- Matrix of hyaluronic acid with multiple layers: multi-molecular hyaluronic acid delivers hydration at multiple depths by plumping lines caused by dehydration on the surface while maintaining moisture stores in the deeper layers.
- Vitamin B3 (niacinamide), panthenol, and allantoin act together to reduce hyperpigmentation, soothe the tingling that follows stimulation, and help to reinforce the integrity of the skin barrier.
Clinical Expert Insight
In clinical practice, achieving deep dermal delivery of high-molecular-weight peptides without resorting to invasive methods has long been a major objective. IDENEL’s micro-spicule technology successfully solves this issue. The micro-tingling sensation felt when the product is applied is the active biological indicator, indicating that the spicules are forming micro-channels to deliver the peptides. This treatment is excellent for use as a maintenance procedure between clinic visits or as a more intensive at-home care routine for skin that needs structural restoration.
— Sabine Lepere, Aesthetic Practitioner, Phlebotomist & Founder of Windsor Mews Clinic
One More Thing to Consider…….
Optimise your skin from within: Identify internal hormone, thyroid, and vitamin markers that influence collagen renewal in your skin with our painless Tasso+ at-home blood collection kit.
How to Apply – Professional Protocol
- Clean the skin thoroughly first, then use your main soothing toner or light essence.
- Put a small amount, about the size of a pea, from the syringe applicator directly onto the areas in question (such as the lines around the eyes, the forehead lines, the smile lines, or the neck).
- Press and roll the cream into the skin with your fingertips, without rubbing it aggressively; a slight prickling or tingling is entirely normal and indicates that the spicules are penetrating.
- Use it only at night, and at first every 2 to 3 days so that the skin can get used to it, increasing the frequency as tolerated or as recommended by your practitioner.
- When using active ingredients based on spicules, you should consistently apply a broad-spectrum SPF. This is essential daytime protection: Shield newly regenerated skin and prevent photo-ageing following active spicule treatments.
Research & Clinical References
- Transdermal Sponge Spicule Delivery: Microscopic marine spicules as natural transdermal delivery systems
- Niacinamide & Skin Barrier Function: Clinical studies on topical Vitamins in photoaged skin – Journal of Cosmetic Dermatology / Wiley Online Library
- Peptides in Anti-Ageing Therapeutics: Mechanisms of topical peptide signalers in neocollagenesis – Modern Aesthetics












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