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How to Apply Adipeau
Welcome to the UK’s leading official Adipeau stockist! Here, you’ll find everything you need to know about using Adipeau Volume Cream for optimal results.
For best results with Adipeau Volume Cream, remember this crucial rule: don’t rub it in!
Instead of rubbing, gently “finger paint” the cream onto your skin. This unique application method is key because Adipeau’s natural active ingredients need to slide down your skin’s nearly invisible hair follicles to reach the deeper root structure. Rubbing can trap these beneficial ingredients in the outer layers of your skin, preventing them from working effectively. Finger painting allows the cream the time and access it needs to penetrate where it’s most effective.
Adipeau Volume Cream is designed to address deep lines, especially in delicate areas like around the eyes. While some users report improvements in just a few days, it’s important to manage your expectations and understand that consistent, long-term use is essential for optimal outcomes.
Unlike “overnight” solutions, Adipeau requires dedicated daily application, both morning and night. Most users begin to notice changes around the 4–6 week mark, with more significant improvements typically observed after approximately 10 weeks.
Remember, your skin has an incredible capacity for regeneration, but it requires patience and dedication. Think of Adipeau as part of your “facial fitness” routine. For the best results, it’s vital to integrate Adipeau with other healthy lifestyle practices, including a balanced diet, regular exercise, proper sun care, and a comprehensive skincare regimen. These elements work synergistically to help you achieve your best “facial fitness.”
Ready to start your Adipeau journey, or do you have more questions about achieving your skincare goals?
For those wondering about compatibility with retinol or Retin-A, it can be confirmed that Adipeau Volume Cream can be used in conjunction with these vitamin-A derivatives. Many customers have successfully incorporated the cream into their skincare routines without issues.
Dr. Ivan Galanin, a leading expert in facial plastic and reconstructive surgery in Manhattan, is pioneering new approaches to facial fitness. His groundbreaking research focuses on harnessing the skin’s remarkable regenerative abilities to enhance both facial and full-body wellness. Published in the prestigious journal Aesthetic Plastic Surgery, Dr. Galanin’s work builds upon a distinguished career in scientific innovation.
Before establishing his practice on the Upper East Side, Dr. Galanin founded two successful biotech companies. One developed a treatment for the rare paediatric genetic disease, Farber’s disease, while the other created personalized drug combinations for colon cancer. His scientific training in inflammation research at Sanofi laid the foundation for his current focus on skin regeneration.
Dr. Galanin is a proud member of the American Academy of Facial Plastic and Reconstructive Surgery. Discover how his cutting-edge research can help you achieve your facial fitness goals.
These questions may seem simple but many people, including many practitioners, would struggle to answer them correctly.
Yes, dermal white adipose cells are unique to the skin.
Cite
Driskell RR, Jahoda CA, Chuong CM, Watt FM, Horsley V. Defining dermal adipose tissue. Exp Dermatol. 2014 Sep;23(9):629-31. doi: 10.1111/exd.12450. PMID: 24841073; PMCID: PMC4282701.
No, new fat cells are constantly being made to replace ones that die.
Cite
Nguyen HP, Lin F, Yi D, Xie Y, Dinh J, Xue P, Sul HS. Aging-dependent regulatory cells emerge in subcutaneous fat to inhibit adipogenesis. Dev Cell. 2021 May 17;56(10):1437-1451.e3. doi: 10.1016/j.devcel.2021.03.026. Epub 2021 Apr 19. PMID: 33878347; PMCID: PMC8137669.
Yes, dermal adipocytes have unique regenerative powers.
Cite
Chon SH, Pappas A. Differentiation and characterization of human facial subcutaneous adipocytes. Adipocyte. 2014 Nov 14;4(1):13-21. doi: 10.4161/21623945.2014.955402. PMID: 26167398; PMCID: PMC4496965.
In the lower dermis, in and around the vellus hair follicles.
Cite
Nicu C, Pople J, Bonsell L, Bhogal R, Ansell DM, Paus R. A guide to studying human dermal adipocytes in situ. Exp Dermatol. 2018 Jun;27(6):589-602. doi: 10.1111/exd.13549. PMID: 29603400.
There is no separation between dermal and subcutaneous adipocytes.
Cite
Nicu C, Pople J, Bonsell L, Bhogal R, Ansell DM, Paus R. A guide to studying human dermal adipocytes in situ. Exp Dermatol. 2018 Jun;27(6):589-602. doi: 10.1111/exd.13549. PMID: 29603400.
Immature fat cells or pre-adipocytes are more numerous than the mature fat cells.
Cite
Roberta Florido, Tamara Tchkonia, James L. Kirkland, Chapter 5 – Aging and Adipose Tissue, Editor(s): Edward J. Masoro, Steven N. Austad, In Handbooks of Aging, Handbook of the Biology of Aging (Seventh Edition), Academic Press, 2011, Pages 119-139, ISBN 9780123786388
Yes, small molecules less than 500 daltons are readily able to reach the skin’s fat cells via the hair follicle path.
Cite
Abd E, Benson HAE, Roberts MS, Grice JE. Follicular Penetration of Caffeine from Topically Applied Nanoemulsion Formulations Containing Penetration Enhancers: In vitro Human Skin Studies. Skin Pharmacol Physiol. 2018;31(5):252-260. doi: 10.1159/000489857. Epub 2018 Jul 12. PMID: 30001555.
Yes, as adipocytes become large they stop promoting adipogenesis and start suppressing adipogenesis.
Cite
Stenkula KG, Erlanson-Albertsson C. Adipose cell size: importance in health and disease. Am J Physiol Regul Integr Comp Physiol. 2018 Aug 1;315(2):R284-R295. doi: 10.1152/ajpregu.00257.2017. Epub 2018 Apr 11. PMID: 29641234.
Yes, large adipocytes instruct fibroblasts to reduce collagen, elastin and hyaluronic acid production by up to 80 percent.
Cite
Ezure T, Amano S. Negative regulation of dermal fibroblasts by enlarged adipocytes through release of free fatty acids. J Invest Dermatol. 2011 Oct;131(10):2004-9. doi: 10.1038/jid.2011.145. Epub 2011 Jun 23. PMID: 21697886.
Yes, KPE reduces cell size by stimulating fat cells to release lipid.
Cite
Okabe Y, Shimada T, Horikawa T, Kinoshita K, Koyama K, Ichinose K, Aburada M, Takahashi K. Suppression of adipocyte hypertrophy by polymethoxyflavonoids isolated from Kaempferia parviflora. Phytomedicine. 2014 May 15;21(6):800-6. doi: 10.1016/j.phymed.2014.01.014. Epub 2014 Mar 11. PMID: 24629599.
Yes, safflower seed oil is made of mostly long chain linoleic and oleic fatty acids.
Cite
Deliorman Orhan D, Pekacar S, Ulutaş OK, Özüpek B, Sümmeoğlu D, Berkkan A. Assessment of Commercially Safflower Oils (Carthami Oleum Raffinatum) in Terms of European Pharmacopoeia Criteria and Their Weight Control Potentials. Turk J Pharm Sci. 2022 Jun 27;19(3):273-279. doi: 10.4274/tjps.galenos.2021.84484. PMID: 35775241; PMCID: PMC9254086.
Yes, long chain fatty acids increase conversion of pre-adipocytes significantly.
Cite
Kokta TA, Strat AL, Papasani MR, Szasz JI, Dodson MV, Hill RA. Regulation of lipid accumulation in 3T3-L1 cells: insulin-independent and combined effects of fatty acids and insulin. Animal. 2008 Jan;2(1):92-9. doi: 10.1017/S1751731107000936. PMID: 22444967.
Yes, topically applied KPE penetrates readily into the dermal white adipose tissue.
Cite
Tuntiyasawasdikul S, Limpongsa E, Jaipakdee N, Sripanidkulchai B. Transdermal permeation of Kaempferia parviflora methoxyflavones from isopropyl myristate-based vehicles. AAPS PharmSciTech. 2014 Aug;15(4):947-55. doi: 10.1208/s12249-014-0122-y. Epub 2014 May 3. PMID: 24789664; PMCID: PMC4113614.
Yes, topically applied long-chain fatty acids penetrate readily into the dermal white adipose tissue.
Cite
Raufast V, Mavon A. Transfollicular delivery of linoleic acid in human scalp skin: permeation study and microautoradiographic analysis. Int J Cosmet Sci. 2006 Apr;28(2):117-23. doi: 10.1111/j.1467-2494.2006.00303.x. PMID: 18492146.
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